Dr. Ekperechi Sabinus Amadi

B Sc., M Sc., PhD.

Ekperechi Sabinus Amadi,    PhD

Senior Lecturer



The discovery of antibiotics many years ago marked a major milestone in the history of microbial disease treatment and control. However, the emergence and re-emergence of antibiotic-resistant strains of most pathogenic organisms, particularly in recent times, has posted a big challenge to the management of infectious diseases. Dr. Amadi and co-workers had over the years determined the prevalence rate of some pathogens in Eastern Nigeria and their susceptibility to commonly used antibiotics. The occurrence of Extended spectrum Beta-lactamase (ESBL) enzymes among the resistant pathogens as well as their molecular characterization has been ascertained in some cases and still ongoing. Further, the effect of crude medicinal plant extracts on some isolated resistant pathogens has been conducted. Further determination and characterization of these extracts are still on course. Newcastle Disease (ND) remains a paramount problem to the poultry industry in Nigeria. In this regard, the occurrence rate of Newcastle disease virus has been determined in some areas of Eastern Nigeria as well as the effects of local adjuvant. Further efforts in the area of vaccine delivery techniques and identification of lentogenic/avirulent strains of the virus are our current interest. In Nigeria, public health parasitic diseases have remained a big threat to the populace over the years. Efforts to determine their actual spread and distribution are vital to their prevention and control. Dr. Amadi and colleagues have previously determined the prevalence and prevention strategies of some common public health diseases such as malaria. The current research interest is in hand hygiene practices among different categories of people and indigenization of hand hygiene in public and private places.

Academic and Professional Qualifications

  • ♦  PhD, 2004, Medical Microbiology, Nnamdi Azikiwe University, Awka, Nigeria.
  • ♦  M.Sc, 1995, Microbiology (Medical Virology), University of Nigeria Nsukka, Nigeria.
  • ♦  B.Sc (Hons), 1990, Microbiology, Imo State University, Okigwe, (Now, Abia State University, Uturu, Nigeria)
  • ♦  Certificate, 1994 HIV/AIDS Education (AFRICARE)
  • ♦  Certificate, 1995 HIV Management, Monitoring and Evaluation (WHO)

Membership of Professional bodies

  • ♦  Member, Nigeria Society for Microbiology (NSM).
  • ♦  Member, National Publicity Secretary (PRO), NSM 2010- Date
  • ♦  Member, Biotechnology Society of Nigeria (BSN).
  • ♦  Member, Foundation for African Development through International Biotechnology (FADIB).
  • ♦  Member, American Society for Microbiology (ASM).

  • ♦  Lecturer II, Department of applied microbiology, Ebonyi State University Abakaliki, Nigeria 1998.
  • ♦  Lecturer I, Department of applied microbiology, Ebonyi State University, Abakaliki, Nigeria 2002.
  • ♦  Senior Lecturer, Department of microbiology, Ebonyi State University, Abakaliki, Nigeria 2005.
  • ♦  Head, department of applied microbiolgy, Ebonyi State University, Abakaliki Nigeria, 2001 – 2005.

  • Iroegbu, C.U and Amadi, E.S (2004). Ecological and Serological Evidence of enzootic circulation of Newcastle Disease virus strains among free-roaming avian species in Nsukka environment, Nigeria. Bull. Anim. Hlth. Prod. Afr. 52(1) : 13-20. ISSN : 0378-9721

  • Nwakpu, K.O., Ezeifeka, G.O., Amadi, E.S and Uneke, C.J (2004). Screening of Anthoclesta djalonensis, Nauclea latifolia and Zanthoxylum species for antibacterial activity. Journal of Health and Visual Sciences. 6(1): 39-43. ISSN : 1119-2006.

  • Uneke, C.J., Jagun, B.I., Duhlinska, D.D., Nwakpu, K.O and Amadi, E.S (2004). Assessment of clinical acquired Toxoplasmosis using Toxoplasma gondii Igg-ELISA in human Immunodeficiency virus(HIV) infected patients in Jos, Nigeria. World Journal of Biotechnology, 5(1): 790-795. ISSN : 1119-0957.

  • Uneke, C.J., Mafuyai, H.B., Njoku, O.M., Chuga, G and Amadi, E.S (2004). Prevalence of sub-urban intestinal Schistosomiasis in Jos, Nigeria. Journal of Biomedical Sciences in Africa, 2(1): 59-61. ISSN : 1597-216X.

  • Inyama, P.U., Uneke, C,J., Anyanwu, G.I., Idoko, J.H and Amadi, E.S (2004). Carriage rate of hepatitis B surface antigen (HBsAg) in HIV infected patients In Jos, Nigeria. Journal of Health and Visual Sciences. 6(3): 171-175. ISSN : 1119-2006.

  • Ogbu, O., Amadi, E.S and Sobka, U.A (2004). Detection of antibody against Newcastle Disease virus among free roaming pigeons in Agege, Lagos, Nigeria. Journal of Biomedical Sciences in Africa. 2(2): 45-46. ISSN : 1597-216X.

  • Uneke, C.J., Inyama, P.U., Anyanwu, G.I., Idoko, J.H., Amadi, E.S and Ngwu, M.E (2005) Malaria and HIV co-infection in Jos, Plateau: Implication for Malaria control Journal of Biomedical Sciences in Africa. 3(1): 10-12. ISSN : 1597-216X.

  • Amadi, E.S., Uneke, C.J., Elom, S.O and Olabamiji, S.O (2005). Treatment of skin infection with traditional black soap: in vitro effect on Staphylococcus aureus. Journal of Health and Visual Sciences. 7(2): 72-75. ISSN : 1119-2006.

  • Ogbu, O., Nworie, O., Echeonwu, G.O.N and Amadi, S.E (2006). Isolation and characterization of Newcastle Disease Virus and its potential for development of thermostable vaccine for tropical climate. Journal of Information, Communication and Computing Technologies. 2(2): 134-138. ISSN : 0794- 6910

  • Amadi, E.S., Enemuo, O.B., Uneke, C.J., Nwosu, O.K., Onyeagba, R.A and Ugbogu,O.C (2007). Asymptomatic bacteriuria among pregnant women in Abakaliki, Ebonyi State, Nigeria. Journal of Medical Sciences. 7(4): 698-700. ISSN : 1682-4474. http://www.ansinet.org/jms.

  • Amadi, E.S., Oyeka, C.A., Onyeagba, R.A., Ugbogu, O.C and Okoli, I (2007). Antimicrobial screening of Breynia nivosus and Ageratum conyzoides against Dental caries organism. Journal of Biological Sciences. 7(2): 354-358. ISSN : 1727-3048. http://www.ansinet.org/jbs

  • Amadi, E.S., Oyeka, A., Onyeagba, R.A., Okoli, I and Ugbogu, O.C (2007). Studies on the antimicrobial effects of Spondias mombin and Baphia nitride on Dental caries organism. Pakistan Journal of Biological Sciences, 10(3): 393-397. ISSN : 1028-8880. http://www.pjbs.org

  • Orji, I., Ezeifeka, G., Amadi, E.S and Okafor, F (2007). Role of Enriched media in bacterial isolation from semen and effects of microbial infection on semen quality: a study on 100 infertile men. Pakistan Journal of Medical Sciences, 23(6 ): 885-888. ISSN : 1682-024X. http://www.pjms.com.pk

  • Amadi, E.S., Nwosu, O.K., Ekekwe, J.O and Iroha, I.R (2007) Asymptomatic urogenital tract infections among pregnant women in Abakaliki, Ebonyi State, Nigeria. Journal of Applied and Natural Sciences. 2(1) : 15-18. ISSN : 2006- 411X.

  • . Ikeagwu, I.J., Amadi, E.S and Iroha, I.R (2008). Antibiotic sensitivity pattern of Staphylococcus aureus in Abakaliki, Nigeria. Pakistan Journal of Medical Sciences . 24(2):231-235. ISSN : 1682-024X. http://www.pjms.com.pk

  • Iroha, I.R., Adikwu, M.U., Amadi, E.S ., Aibinu, I., Esimone, C.O., (2008). Characterisation of Extended Beta-Lactamase producing E. coli from secondary and tertiary hospitals in South Eastern Nigeria. Research Journal of Microbiology, 3( 7): 514-519. ISSN : 1816-4935 http://www.academicjournals.net/jm DOI: 10.3923/jm.2008.514.519

  • Iroha, I.R., Amadi, E.S., Orji, J.O and Esimone, C.O (2008). In vitro evaluation of the activity of colloidal silver concentrate against Pseudomonas aeruginosa isolated from postoperative wound infection. Scientific Research and Essay, 3(5): 209-211. ISSN : 1992-2248. http://www.academicjournals.org/SRE

  • Amadi, E.S., Oyeka, C.A., Okoli, I., Ihedioha, J.I and Iroha, I.R (2009). Dental caries inhibition in albino rats by Breynia nivosus extract. Research Journal of Medicinal Plants.3(1): 1-8. ISSN : 1819-3455. http://www.academicjournals.net/rjmp

  • Ogbu, O., Agumadu, N., Uneke, C.J and Amadi, E.S (2008). Aetiology of acute infantile Diarrhea in the southeastern Nigeria: An assessment of Microbiological and antibiotic sensitivity profile. The Internet Journal of Third World Medicine. Volume 7, Number 1. ISSN : 1539-4646. http://www.ispub.com/ostia/index.php?xm1File path=journals/ijtwm/front.xml.

  • Iroha, I.R., Amadi, E.S., Adikwu, M.U and Esimone, C,O (2008). Detection of plasmid Borne extended-spectrum beta-lactamase enzymes in clinical isolates of Escherichia coli from a community General Hospital. International Journal of Molecular Medicine and Advanced Sciences. 4(2): 45-48. ISSN 1813-176X. http://www.medwelljournals.com/ijmmas.

  • Iroha, I.R., Esimone, C.O and Amadi, E.S (2008).A comparative study on the prevalence of malaria parasite among HIV seropositive and seronegative individuals in Abakaliki Nigeria. African Journal of Clinical and Experimental Microbiology. 9(3): 136-141 ISSN: 1595-689X . http://www.ajol.info/journals/ajcem

  • Nwaziri, A.A., Ezeifeka, G.O and Amadi, E.S (2008). Susceptibility of Laboratory Rodents and Chicks to colonization with Gardnerella vaginalis. Canadian Journal of Pure and Applied Sciences. 2(3) : 547-550. ISSN : 1715-9997. http://www.cjpas.net

  • Iroha, I.R., Amadi, E.S., Orji, J.O., Agabus, A.C., Oji, A.E and Esimone, C.O (2008). The interaction between Gentamicin and Floroquinolones against extended spectrum beta lactamase (ESBL) producing clinical isolates of Escherichia coli. Trends in Medical Research. 3 (2): 90-94. ISSN : 1819-3587. DOI: 10.3923/tmr.2008.90.94 http://www.academicjournals.net/tmr

  • Iroha, I.R., Amadi, E.S., Agabus, A.C and Oji, A.E (2008). Susceptibility pattern of Extended spectrum Beta Lactamase producing Klebsiella pneumoniae from clinical isolates. The Internet Journal of Microbiology, 5(2): ISSN : 1937-8289 http://www.ispub.com/ostia/index.php?xmlFilepath=journals/ijmb/current.xml

  • Amadi, E.S., Iroha, I.R., Odeta, N.P., Ilang, D.C., Chime, E.C., Umeatuenyi, K.C and Ayogu, T.E (2008). Microbial Reduction and Coagulation study on turbid Onuebonyi River Abakaliki using Moringa oleifera seeds. Nigerian Journal of Microbiology, 22(1): 1759-1763. ISSN: 0794-1293 http://www.nsmjournal.org

  • Ezeifeka, G.O., Nzewi, K.P and Amadi, E.S (2008). Effect of oil adjuvanted Newcastle Disease vaccine on immune response in chickens. Nigerian Journal of Microbiology 22(1): 1754-1758. ISSN : 0794-1293 http://www.nsmjournal.org

  • Onyido, A.E., Okolo, P.O., Obiukwu, M.O and Amadi, E.S (2009). A survey of vectors of Public Health Diseases in un- disposed refuse dumps in Awka town, Anambra State, Southeastern Nigeria. Research Journal of Parasitology. 4(1):22- 27. ISSN : 1816-4943. http://www.academicjournals.net/rjp

  • Amadi, E. S., Oyeka, C.A., Okoli, I., Ihedioha, J.I and Iroha, I.R (2009). Anticaries effects of Baphia nittida extract in albino rats. European Journal of Dentistry and Medicine 1(1): 1-7 ISSN 1996-3378. http://www.scialert.net/ejdm. DOI: 10.3923/ejdm.2009.1.7

  • Amadi, E.S., Uzoaru, P.N., Orji, I., Nwaziri, A.A and Iroha, I.R (2009). Antibiotic Resistance in clinical isolates of Pseudomonas aeruginosa in Enugu and Abakaliki, Nigeria:The Internet Journal of Infectious Diseases; 2 (1) http://www.ispub.com/ostia/index.php?xmlPrinter=true&xmlFilePath=Journals/ijid

  • Ayogu, T.E and Amadi, E.S (2009). Studies on the antibacterial activities of medicinal plants on Typhoid fever organism. The Internet Journal of Third World Medicine; Volume 7, Number 2. . ISSN : 1539-4646 http://www.ispub.com/ostia/index.php?xmlPrinter=true&xmlFilePath=journals/ijtwm

  • Iroha, I.R., Ezeifeka, G.O., Amadi, E.S and Umezurike, C.R (2009). Occurrence of Extended Spectrum Beta Lactamase producing Resistant Escherichia coli and Klebsiella pneumoniae in clinical isolates and associated risk factors. Research Journal of Biological Sciences. 4(5): 588-592. ISSN : 1815-8846. http://www.medwelljournals.com/rjbs

  • Iroha, I.R., Amadi, E.S., Nwuzo, A.C and Afiukwa, F.N (2009). Evaluation of the antibacterial activity of extracts of Sida acuta against clinical isolates of Staphylococcus aureus isolated from Human immunodeficiency virus/acquired immunodeficiency syndrome patients. Research Journal of Pharmacology. 3(2): 22-25 http://www.medwelljournals.com/rjp

  • Iroha, I.R., Adikwu, M.U., Esimone, C.O., Aibinu, I and Amadi, E.S (2009). Extended spectrum beta-lactamase (ESBL) in E. coli isolated from a tertiary hospital in Enugu State, Nigeria. Pakistan Journal of Medical Sciences. 25(2): 279-282. ISSN : 1682-024X. http://www.pjms.com.pk

  • Amadi, E.S., Ononiwu, C.E., Aballa, N., Oladimeji, S.A., Aneke, F.A., Aneke, C.O and Azeez, OMF (2009). Seroprevalence of Human Immunodeficiency Virus among patients attending Federal Dental Clinic Enugu, Nigeria. Internet Journal of Dental Science . Volume 7 Number 2 ISSN: 1937-8238 http://www.ispub.com/ostia/index.php?xmlPrinter=true&xmlFilePath=journals/ijds

  • Ozumba, N.A., Onyido, A.E., Nwosu, E.O., Ekwunife, C.A and Amadi, E.S (2009). Field Trials Test on the efficacy and Residual effect of Bistar R 10wp on Mosquitoes and other household arthropod pests. The Internet Journal of Tropical Medicine. Volume 6, No. 1. http://www.ispub.com/ostia/index.php?xmlPrinter=true&xmlFilePath=journals/ijtm

  • Onyido, A.E., Ezike, V.I., Ozumba, N.A., Nwosu, E.O., Ikpeze, O.O., Obiukwu, M.O and Amadi, E.S (2009). Crepuscular Man-Biting Mosquitoes of a Tropical Zoological Garden in Enugu, South Eastern Nigeria. The Internet Journal of Parasitic Diseases. Volume 4, No. 1. http://www.ispub.com/ostia/index.php?xmlPrinter=true&xmlFilePath=journals/ijpd

  • Amadi, E.S., Ononiwu, C.E., Aballa, N., Oladimeji, S.A., Aneke, F.A and Aneke, C.O (2009). The Epidemiology of Hepatitis C virus infection among patients attending the Federal Dental Clinic Enugu. Trends in Medical Research. 4(4): 91-95. ISSN: 1819-3587. http://www.academicjournals.net/tmr

  • Onyido, A.E., Deezia, N.P.L., Obiukwu, M.O and Amadi, E.S (2009). Ecology of Man-Biting Mosquitoes in the development site of Nnamdi Azikiwe University, Awka, Anambra State, Southeastern Nigeria. The Internet Journal of Health, Volume 9, No. 2. http://www.ispub.com/ostia/index.php?xmlPrinter=true&xmlFilePath=journals/ijh

  • Iroha, I.R., Amadi, E.S., Oji, A.E., Nwuzo, A.C and Ejike-Ugwu, P.C (2010). Detection of Plasmid Borne Extendede spectrum Beta lactamase enzymes from blood and urine Isolates of Gram negative bacteria from a University Teaching Hospital in Nigeria. Current Research in Bacteriology, 3(2): 77-83. ISSN: 1994-5426. http://www.ansinet.org/crb

  • Nwaziri, A.A., Ezeifeka, G.O and Amadi, E.S (2010). The effect of Gardnerella vaginalis on infertility and pregnancy of albino rats. The Internet Journal of Gynecology and Obstetrics. Vulume 12, Number 2 http://www.ispub.com/ostia/index.php?xmlPrinter=true&xmlFilePath=journals/ijgo

  • Onyido, A.E., Ozumba, N.A., Ezike, V.I., Nwosu, E.O., Chukwuekezie, O.C and Amadi, E.S (2010). Surveillance studies of Aedes stegomyia Mosquitoes in three ecological locations Of Enugu, South-Eastern Nigeria. The Internet Journal of Infectious Diseases.Volume 8, Number 1 http://www.ispub.com/ostia/index.php?xmlPrinter=true&xmlFilePath=journals/ijid.

  • Amadi, E.S and Oyibo, P.G (2010). The impact of Maternal Malaria Parasitaemia on Pregnancy outcomes in Abakaliki, Ebonyi State, Nigeria. Nigerian Journal of Microbiology, 24(1): 2038-2042. ISSN 0794-1293. http://www.nsmjournal.org

  • Onyido, A.E., Agbata, V.O., Umeaneto, P.U., Obiukwu, M.O and Amadi, E.S (2010). Malaria burden and Vector Abundance in a sub-urban community in the rainforest Zone of Nigeria. Nigerian Journal of Microbiology, 24(1): 2224-2230 ISSN 0794-1293. http://www.nsmjournal.org

  • Okonkwo, E.C., Amadi, E.S., Idioha, J.C., Nworie, O., Nwuzo, A.C and Onwe, J.C (2010). Prevalence of Trichomonas vaginalis among pregnant women in Abakaliki, Ebonyi State. International Journal of Current Research, 11:011-015. ISSN : 0975-833X. http://www.journalcra.com

  • Oyibo, P.G., Amadi, E.S and Nwonwu, E.U (2010). Prevalence of Malaria Parasitaemia and Malaria related Anaemia among Parturients in Abakaliki, South East Nigeria. Journal of Biomedical Sciences in Africa, 8(1&2): 62-70. ISSN: 1597-216K

  • Chikwendu, C.I., Amadi, E.S and Obi, R.K (2010). Prevalence and antimicrobial resistance in Pseudomonas aeruginosa and Klebsiella pneumoniae isolates from non- Clinical urine samples. New York Science Journal, 3(11): 194- 200. ISSN : 1554-0200. http://www.sciencepub.net

  • Iroha, I.R., Oji, A.E., Nwosu, O.K and Amadi, E.S (2011). Antimicrobial activity of Savlon, Izal and Z-Germicide against clinical isolates of Pseudomonas aeruginosa from Hospital wards. European Journal of Dentistry and Medicine. 3(1): 32-35. ISSN 1996-3378. http://www.scialert.net/ejdm.

  • Amadi, E.S., Ononiwu, C.E., Aballa, N., Oladimeji, S.A., Sofoluwe, K.B., Omale, J.J., Aneke, F.A., Chikwendu, C.I and Onyido, A.E (2011). Hepatitis B and C Virus Co-infections Among Human Immunodeficiency Virus (HIV) infected Patients in Enugu, Nigeria. New York Science Journal, 4(6): 72-76. ISSN: 1554-0200 http://www.sciencepub.net/newyork.

  • Onyido, A.E., Ozumba, N.A., Ezike, V.I., Nwosu, E.O., Amadi, E.S., Obiukwu, M.O., Chukwuekezie, O.C and Umeanaeto, P.U (2011). Breeding and Biting activities of Yellow Fever Mosquitoes in two urban communities with dilapidating infrastructures. Nature and Science, 9(9): 93-98. ISSN:1545-0740 http://www.sciencepub.net.

  • Onyido, A.E., Azubuike, J., Amadi, E.S., Obiukwu, M.O., Ozumba, N.A and Ikpeze, O.O (2011). A survey of Public Health Disease Vectors Breeding in Refuse Dumps in Onitsha Metropolis, Anambra State, Nigeria. New York Science Journal, 4(9): 34-39. ISSN: 1554-0200. http://www.sciencepub.net/newyork.

  • Onyido, A.E., Amadi, E.S., Olofin, I., Onwumma, A.A., Okoh, I.C and Chikwendu, C.I (2011). Prevalence of Entamoeba gingivalis and Trichomonas tenax among dental patients Attending Federal School of Dental Technology and Therapy Clinic Enugu, Nigeria. Nature and Science, 9(9): 59-62. ISSN: 1545-0740, http://www.sciencepub.net.

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