Samuel Chidiebere Uzoechi

SC Uzoechi

Samuel Chidiebere Uzoechi

1650 NE Valley Road Apt L2
Pullman, WA 99163
Email:  samuel.uzoechi@wsu.edu, s.c.uzoechi@gmail.com
Telephone: (509) 592-1888

PROFILE

Ingenieur Samuel Chidiebere Uzoechi is a scientist and an entrepreneur who wants to move his idea from laboratory to the world. He obtained B.Tech in Biomedical Technology with Professor Chuba Okoye at the Federal University of Technology, Owerri. He moved to the Netherlands in 2010 and obtained MSc in Biomedical Engineering (Cell and Tissue Engineering) with Professor Marcel Karperien at the University of Twente. He is currently a PhD candidate in the Lab of Professor Nehal Abu-Lail at Washington State University. His MSc research focused on the effect of nutrient gradients on tissue engineered cartilage. He’s currently investigating how bacterial cells modify their surfaces to enhance their resistance to antibiotics. This work has potential applications in the medical and pharmaceutical industries. His skills include biomaterials characterization, AFM and SEM techniques, PCR, mammalian and bacterial cell culture. I am seeking to build a long-term collaboration in biomedical engineering with an organization that enables me to learn and implement new technologies for the betterment of the healthcare practice, utilize my education, skills, and experiences, and which will also provide me with the opportunity for growth and advancement.

 


EDUCATION

  • Washington State University, Pullman    –  2015 – Present

PhD Bioengineering (Bacterial Adherence, Multidrug Resistance, and Biofilm Technology)

  • The University of Twente, the Netherlands    –     2010 – 2012

MSc Biomedical Engineering (Molecular, Cellular & Tissue Engineering)

  • Federal University of Technology, Owerri, Nigeria     –     2003 – 2009

B.Tech Biomedical Technology (Clinical and Rehabilitation Technology)

  • University of Calabar, Calabar-Nigeria    –      2001 – 2003

National Diploma in Science Laboratory Technology

WORK SKILLS AND EXPERIENCE:

  • Atomic Force Microscope, Scanning Electron Microscope and Confocal/Fluorescence Microscope
  • Mammalian and Bacterial Cell Culture, and Persister Cells Isolation
  • Biofilm Technology
  • Mammalian RNA Isolation and Real-Time Polymerase Chain Reaction (RT PCR), Transfection assay etc
  • Data Analysis (Origin and SigmaPlot)
  • Histological staining (Collagen, GAG, Cell Viability), DNA isolation and quantification
  • General Laboratory assay (DNA, GAG, ELISA, metabolites, ALP, Calcium Phosphate)
  • Metabolic Analyses (Glucose, Lactate etc)
  • Perform in Vitro Cell-Based Biochemical and Phenotypic Assays, Gel Electrophoresis,
  • Biomaterials Fabrication and Characterization
  • Read Science Literature and Design Protocols Regarding New Experiments and Procedures.
  • Can Perform Assigned Duties Without Constant Supervision
  • Experience with Highly Complex Clinical and/or Research Laboratory Operations

TEACHING EXPERIENCE:

  • Introduction to biomedical engineering
  • Biomaterials and tissue engineering
  • Controlled drug and gene delivery
  • Stem cells in regenerative medicine
  • Introduction to biopharmaceutical engineering
  • Supervision of undergraduate projects

AREAS OF RESEARCH INTEREST:

I specialized in the areas of surface modification of orthopaedic implants, controlled drug delivery, and biomaterials for soft and hard tissue engineering. My prime interests lie in the areas of tissue engineering and stem cells in regenerative medicine. Currently, I am working on different projects such as the investigation of the effects of nutrient gradients on tissue-engineered cartilage, the architecture of tissue engineering constructs on nutrient supply and cell behaviour and optimization of techniques for in-vitro expansion of stem cells. In the area of controlled drug delivery, I am developing new techniques for polymeric vectors for intracellular protein delivery for malaria treatment. I am also investigating the role of bacterial surface biopolymers, cell elasticity, morphology and adhesion, membrane permeability and biofilm formation on bacterial resistance to ampicillin.

AWARDS:

  • American Society of Microbiology Student and Postdoctoral Travel Award AAR 2018
  • National Institute of Health (NIH), 2015-2017
  • Melvin and Ruth Scholarship, Fall 2017
  • Faculty of Science and Technology, University of Twente Master’s Award 2012
  • Imo State Government of Nigeria Scholarship Award 2012

PROFESSIONAL MEMBERSHIPS:

  • Society for Tissue Engineering and Regenerative Medicine of Nigeria (STERMN)
  • American Institute of Chemical Engineers (AIChE)
  • Biomedical Engineering Society (BMES)
  • Tissue Engineering and Regenerative Medicine International Society (TERMIS)
  • North Texas Biomedical Association, USA
  • Nigerian Institute for Science Laboratory Technology (NISLT)
  • Nigerian Institute for Biomedical Engineering (NIBE)

PUBLICATIONS AND MANUSCRIPTS IN PREPARATION

  • Somayeh Ramezanian, Samuel Uzoechi, Balasingan Muhunthan, Nehal Abu-Lail; Role of ionic strength in the thicknesses of the biopolymer fringes, spring constants, and Young’s moduli of Pseudomonas putida, Journal of Vacuum Science & Technology B: Vol.36, Issue 2 (16 February 2018).
  • Muodebe Nwokeji, Benjamin Nkem, Raphael Egejuru, Samuel Uzoechi, Ijeoma Ogoamaka, Austin Nnadozie; Cryptosporidiosis Among Human Immunodeficiency Virus-Tuberculosis (HIV-TB) Co-infected Adult Patients Attending a Specialist Hospital in Imo State, South Eastern Nigeria, IJPMR 1, No. 4, 2015, pp. 238-241
  • Samuel C. Uzoechi, Kennedy O. Ejeta, Goddy C. Okoye, Gideon I. Ndubuka, Patrick U. Agbasi, Benjamin I. Nkem; Enhancing Chondrogenesis of Primary Chondrocytes by Exposure to Glucose Gradients, JBBBE Vol. 24 (2015) pp 30-42
  • Patrick Ugochukwu Agbasi, Nse Abasi, Joy Jeremiah Onye, Chinasa Ibeawuchi, Samuel C Uzoechi, Emmanuel Ayoma Alagwu, Chukwubike U Okeke, Godwin C Uloneme, The Effect of Subchronic Low Dose of DDVP And Sodium Azide On The Haematological Indices Of Albino Rats, WJPPS Vol. 4 Issue 04 (2015)
  • Uzoechi, S. C., Okoye, G. C., Ndubuka, G. I., Agbasi, P. U., Nkem, B. I., Ejeta, K. O., Investigation of In Vitro Biological Behavior and Pro-Angiogenic Potential of Baicalein as Hypoxia-Mimicking Agent on Human Osteosarcoma Cell Line, Nig J. Biotech. Vol. 28 (2014) 11-16.
  • Samuel C. Uzoechi, Goddy C. Okoye, Kennedy O. Ejeta, Benjamin I. Nkem, Effect of Strontium Enhanced Calcium Phosphate Coating on In Vitro Behavior of Human Mesenchymal Stem Cell (hMSC ), JBBBE Vol. 21 (2014) pp 35-44
  • Tim W.G.M. Spitters, Carlos Miguel Domingues Mota, Samuel C. Uzoechi, Barbara Slowinska, Lorenzo Moroni, Marcel Karperien, Glucose Gradients Influence Zonal Matrix Deposition in 3D Cartilage Construct, Tissue Engineering Part A. 2014 June 6.
  • Samuel C. Uzoechi, Martins O. Ojiegbe, Goddy C. Okoye, Chuba Okoye, Design and Development of Solar Energized Phototherapy Device for Treatment of Neonatal Jaundice (Tech Thesis, 2009)

 

CONFERENCES, PRESENTATIONS, AND WORKSHOPS

  • Samuel C. Uzoechi and Nehal I. Abu-Lail. Defensive Multidrug-resistant Escherichia coli Surface Modification in Response to Ampicillin, American Institute of Chemical Engineering, Minneapolis, October 2017.
  • Samuel C. Uzoechi and Nehal I. Abu-Lail. Multidrug-resistant Escherichia coli: Measurement of membrane mechanical properties, nanoscale adhesion, and biofilm formation, NIH Biotechnology Training Annual symposium, WSU, April 2017, Pullman, WA
  • Samuel Uzoechi, Tim Spitters, Marcel Karperien, Chrystal Quisenberry, Arshan Nazempour, Arda Gozen, Bernard van Wie and Nehal I. Abu-Lail. Multilayered scaffold complex for osteochondral tissue engineering, Annual Advisory Board Meeting, VSCEB, WSU, May 2015, Pullman, WA
  • Samuel Uzoechi, Tim Spitters, Marcel Karperien, Chrystal Quisenberry, Arshan Nazempour, Arda Gozen, Bernard van Wie and Nehal I. Abu-Lail. Multilayered scaffold complex for osteochondral tissue engineering, NIH Biotechnology Training Annual symposium, WSU, May 2015, Pullman, WA
  • National Effective Teaching Institute: Workshop on Effective Teaching and Cooperative Learning – Washington State University, USA. August 20-121, 2015
  • National Institute of Health Biotechnology: Symposium on Genetic Engineering (Poster Presentation) – Washing State University, USA. May 1, 2015
  • National Institute of Health Biotechnology: Symposium on Protein Evolution (Poster Presentation) – Washing State University, USA. May 1, 2015

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